Mediterranean regions, Meadows, Borders of forests. Milk thistle, or silybum marianum, has been used as a herbal healer since ancient Greek times. Silymarin present in Milk Thistle possesses anti-angiogenic property. The efficacy of Silibin present in this herb against the human hepatocellular carcinoma cells was studied. Silybum marianum (holy thistle, lady’s thistle, milk thistle, St. Mary’s thistle) has been used to treat liver problems, such as hepatitis, and prostatic cancer. The hepatoprotective effect of this herb is beneficial in preventing damage to the liver caused due to the side effects of some medications and additives and preservatives in the food. Silymarin marianum is a plant whose many components, primarily a flavanolignan chemical known as silymarin, have pronounced antioxidant and skin-calming ability. Always take care when taking herbs and Read Our Disclaimer. It has been so dramatically effective that the treatment has never been disputed, even by the traditional medical community.This species is an annual or biennial plant of the Asteraceae family. This action offers protection to the liver cells from the effect of toxins in the body. Silybum marianum is used to treat dyspepsia (heartburn), and is especially effective when used in combination with other plant extracts, such as lemon balm, angelica, peppermint and chamomile. More about Milk Thistle in history Silybum marianum is a familiar thorny plant that’s prickly leaves contain splashes of white, which were historically referred to … Silymarin also has shown benefit in patients with Alzheimer's disease, Parkinson's disease, and cerebral ischemia. is the most researched plant for the treatment of liver disease. The Silybum marianum plant goes by many different names, including Scotch thistle, holy thistle, Mary thistle, variegated thistle, and milk thistle. In the middle ages, the leaves were used in salads, but these days … Milk thistle has some estrogen-like effects that may stimulate the flow of breast milk in women who are breast-feeding infants. It acts as a hepatoprotective agent and prevents damage to the liver cells. The seeds contain silymarin, a group of compounds said to have antioxidant and anti-inflammatory effects. Silybum marianum (SM), a well-known plant used as both a medicine and a food, has been widely used to treat various diseases, especially hepatic diseases. Milk thistle (Silybum marianum) is a flowering herb known for its important medicinal properties. One observational research concluded that a topically-applied, silymarin-based skin cream effectively encourages healthy skin. A European standardized extract of milk thistle was used in most of the trials. Nie należy przekraczać zalecanej porcji do spożycia w ciągu dnia. ... [Effect of Silybum marianum oil and legalon on lipid peroxidation and liver antioxidant systems in rats intoxicated with carbon tetrachloride]. Silibinin strongly inhibited CDC2, CDK2, and CDK4 kinase activity in the cancer cells. Milk-Thistle Herb or Silybum marianum is herbal medicine which is useful in several disorders. Silybum marianum (holy thistle, lady’s thistle, milk thistle, St. Mary’s thistle) has been used to treat liver problems, such as hepatitis, and prostatic cancer. Having been in use as a herbal remedy for over 2000 years, milk thistle is now making a comeback as a popular health aid, and with good reason. The seeds and fruits of SM contain a flavonolignan complex called silymarin, the active compounds of which include silybin, isosilybin, silychristin, dihydrosilybin, silydianin, and so on. Milk Thistle (Silybum Marianum): benefits and virtues of Milk Thistle? It acts as a powerful detoxifier and helps to rebuild the liver cells. Blessed milk thistle,Cardui mariae, Carduus marianum, Holy Thistle, Lady's Thistle, Legalon, Marian Thistle, Mariendistel, Mary Thistle, Mediterranean milk thistle, Our Lady's Thistle, Silimarina, Silybin, Silybum, Silymarin, St. Mary Thistle, Wild Artichoke, variegated thistle and Scotch thistle. Silibinin also caused G1 and G2-M arrest in the Hep3B cells. Uses and Health Benefits of Silybum Marianum Helps protect against cancer Although more studies on Mary thistle’s effects on cancer are still in early stages, it appears that this plant extract can have an inhibitory effect on the expansion of cancer cells and tumors on the skin and can also help prevent cancerous growth in the breast, prostate, and cervix. Photo Gallery It also causes specific receptor interaction and induces modulation of certain cell-signaling pathways such as NF-kappa B. Milk Thistle is commonly used in the treatment of liver disorders. In Europe, milk thistle is a prescribed medication. The cytoprotective action is related to the antioxidative or radical-scavenging effect produced by this herb. It can reduce inflammation (important for people with liver inflammation or hepatitis), and has potent antioxidant effects. These effects are probably related to inhibition of activation of NF-kappa B and the kinases. Origin, composition, the opinion of experts, association with other plants and complementary information on Milk Thistle. The scar tissue reduces the ability of the liver to function optimally and makes the organ hard and lumpy. The active ingredient, or liver-protecting compound in milk thistle is known as silymarin. Milk thistle, known as 'Doodh Patra' has medicinal properties. Milk thistle is a weed, which grows commonly in California and other parts of the world having a warm climate. Known sometimes as Mary thistle or holy thistle, and scientifically as Silybum marianum, milk thistle is a flowering plant originally from the Mediterranean region, although it has been brought to other regions, including North America. Silymarin is the extract of Silybum marianum, or milk thistle, and its major active compound is silybin, which has a remarkable biological effect.It is used in different liver disorders, particularly chronic liver diseases, cirrhosis and hepatocellular carcinoma, because of its antioxidant, anti-inflammatory and antifibrotic power. Silymarin acts as an antioxidant and reduces the free radical production in the body. In animal studies and one small study in humans, milk thistle produced modest reductions in total cholesterol. Topical preparations of milk thistle extract is quite beneficial the skin. Silymarin acts as an antioxidant and reduces the free radical production in the body. An improvement in the liver fibrosis markers was also noticed. Health Benefits of Milk Thistle. You can use this supplement to improve overall health. Milk Thistle is unique in its ability to protect the liver and has no equivalent in the pharmaceutical drug world. 250 ml). However, these results have not been demonstrated in larger human studies. It has been used for thousands of years as a herbal remedy for a variety of ailments, particularly for the liver. It prevents the formation of new blood vessels in the tumor mass. Milk Thistle helps to treat cirrhosis by acting as an anti-inflammatory and hepatoprotective agent. Also known by its scientific name, Silybum marianum, milk thistle grows mostly in California, although it can be grown in many other warm climates as well. Buying Herbs and supplements online offers convenience and greater choice but you need to be vigilant. Silymarin also seems to encourage liver cell growth. The anti-cancer potential of Milk Thistle was evaluated during research. 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